Microwave-assisted solvent-free heterocyclic synthesis

被引：176

作者：

Bougrin, K

Loupy, A

Soufiaoui, M

机构：

[1] Univ Mohammed V Agdal, Dept Chem, Lab Plants Chem & Organ & Bioorgan Synth, Fac Sci, Rabat, Morocco

[2] Paris S Univ, CNRS, UMR 8615, ICMMO,Lab Select React Supports, F-91405 Orsay, France

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS | 2005年 / 6卷 / 2-3期

关键词：

solvent-free reactions; microwave irradiation; heterocycles; 4+2] cycloaddition; 2+2] cycloaddition; 1,3-dipolar cycloaddition; cyclocondensation; combinatorial synthesis;

D O I：

10.1016/j.jphotochemrev.2005.07.001

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In this review, we report the important role of solvent-free conditions coupled with microwave activation and their advantages in heterocyclic synthesis. This eco-friendly approach, which was found application in facile organic synthesis, is applied to the rapid assembly of heteroatom organic compounds via cycloaddition and cyclocondensation reactions. Combinatorial heterocyclic synthesis under solvent-free conditions is described having allowed to build a library of such heterocyclic compounds of pharmacological interest. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：139 / 167

页数：29

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