Synthesis of C2-symmetrical 1,1′-disubstituted ferrocenyl amino alcohols and use in catalytic asymmetric addition of diethylzinc to benzaldehyde

被引：26

作者：

Bastin, S

Delebecque, N

Agbossou, F

Brocard, J

Pélinski, L ^{[1
]}

机构：

[1] Ecole Natl Super Chim Lille, UPRESA 8010, Catalyse Lab, Grp Synthese Organomet, F-59655 Villeneuve Dascq, France

[2] Ecole Natl Super Chim Lille, UPRESA 8010, Catalyse Lab, Grp Chim Organ Appl, F-59655 Villeneuve Dascq, France

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 09期

关键词：

D O I：

10.1016/S0957-4166(99)00181-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Optically active C-2-symmetrical 1,1'-disubstituted ferrocenyl amino alcohols have been used as chiral catalysts in the asymmetric addition of diethylzinc to benzaldehyde. 1-Phenylpropanol has been obtained in up to 83% enantiomeric excess. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：1647 / 1651

页数：5

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