Myocardial Protection Against Ischemia-Reperfusion Injury by GLP-1: Molecular Mechanisms

被引:14
作者
Birnbaum, Yochai [1 ,2 ,3 ]
Ye, Yumei [2 ]
Bajaj, Mandeep [4 ]
机构
[1] Baylor Coll Med, Cardiol Sect, MS BCM, Houston, TX 77030 USA
[2] Univ Texas Med Branch, Dept Biochem & Mol Biol, Galveston, TX USA
[3] St Luke Episcopal Hosp, Texas Heart Inst, Houston, TX USA
[4] Baylor Coll Med, Endocrinol Sect, Houston, TX 77030 USA
关键词
GLUCAGON-LIKE PEPTIDE-1; PROTEIN-KINASE-A; P85 REGULATORY SUBUNIT; NITRIC-OXIDE SYNTHASE; ISOLATED RAT-HEART; ISCHEMIA/REPERFUSION INJURY; CARDIAC-FUNCTION; DIABETIC HEART; INFARCT SIZE; CAMP-PKA;
D O I
10.1089/met.2012.0095
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:387 / 390
页数:4
相关论文
共 45 条
  • [31] A potential role for PTEN in the diabetic heart
    Mocanu, Mihaela M.
    Field, Duncan C.
    Yellon, Derek M.
    [J]. CARDIOVASCULAR DRUGS AND THERAPY, 2006, 20 (04) : 319 - 321
  • [32] RETRACTED: Ischemic preconditioning involves dual cardio-protective axes with p38MAPK as upstream target (Retracted article. See vol. 53, pg. 743, 2012)
    Nagy, Norbert
    Shiroto, Keisuke
    Malik, Gautam
    Huang, Chi-Kuang
    Gaestel, Mathias
    Abdellatif, Maha
    Tosaki, Arpad
    Maulik, Nilanjana
    Das, Dipak K.
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2007, 42 (05) : 981 - 990
  • [33] GLP-1R Agonist Liraglutide Activates Cytoprotective Pathways and Improves Outcomes After Experimental Myocardial Infarction in Mice
    Noyan-Ashraf, Mohammad Hossein
    Momen, M. Abdul
    Ban, Kiwon
    Sadi, Al-Muktafi
    Zhou, Yu-Qing
    Riazi, Ali M.
    Baggio, Laurie L.
    Henkelman, R. Mark
    Husain, Mansoor
    Drucker, Daniel J.
    [J]. DIABETES, 2009, 58 (04) : 975 - 983
  • [34] The cardioprotective and inotropic components of the postconditioning effects of GLP-1 and GLP-1(9-36)a in an isolated rat heart
    Ossum, Alvilde
    van Deurs, Ulla
    Engstrom, Thomas
    Jensen, Jan Skov
    Treiman, Marek
    [J]. PHARMACOLOGICAL RESEARCH, 2009, 60 (05) : 411 - 417
  • [35] GLP-1 and cardioprotection: from bench to bedside
    Ravassa, Susana
    Zudaire, Amaia
    Diez, Javier
    [J]. CARDIOVASCULAR RESEARCH, 2012, 94 (02) : 316 - 323
  • [36] Protein kinase A as another mediator of ischemic preconditioning independent of protein kinase C
    Sanada, S
    Asanuma, H
    Tsukamoto, O
    Minamino, T
    Node, K
    Takashima, S
    Fukushima, T
    Ogai, A
    Shinozaki, Y
    Fujita, M
    Hirata, A
    Okuda, H
    Shimokawa, H
    Tomoike, H
    Hori, M
    Kitakaze, M
    [J]. CIRCULATION, 2004, 110 (01) : 51 - 57
  • [37] Cardioprotective effect afforded by transient exposure to phosphodiesterase III inhibitors - The role of protein kinase A and p38 mitogen-activated protein kinase
    Sanada, S
    Kitakaze, M
    Papst, PJ
    Asanuma, H
    Node, K
    Takashima, S
    Asakura, M
    Ogita, H
    Liao, YL
    Sakata, Y
    Ogai, A
    Fukushima, T
    Yamada, J
    Shinozaki, Y
    Kuzuya, T
    Mori, H
    [J]. CIRCULATION, 2001, 104 (06) : 705 - 710
  • [38] CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
    Shaywitz, AJ
    Greenberg, ME
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1999, 68 : 821 - 861
  • [39] Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart
    Sonne, David P.
    Engstrom, Thomas
    Treiman, Marek
    [J]. REGULATORY PEPTIDES, 2008, 146 (1-3) : 243 - 249
  • [40] Exenatide Reduces Infarct Size and Improves Cardiac Function in a Porcine Model of Ischemia and Reperfusion Injury
    Timmers, Leo
    Henriques, Jose P. S.
    de Kleijn, Dominique P. V.
    DeVries, J. Hans
    Kemperman, Hans
    Steendijk, Paul
    Verlaan, Cees W. J.
    Kerver, Marjolein
    Piek, Jan J.
    Doevendans, Pieter A.
    Pasterkamp, Gerard
    Hoefer, Imo E.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (06) : 501 - 510