Novel Markers of Inflammation in Atherosclerosis

被引：44

作者：

Virani, Salim S. ^{[1
]}

Polsani, Venkateshwar R. ^{[1
]}

Nambi, Vijay ^{[1
]}

机构：

[1] Baylor Coll Med, Dept Med, Houston, TX 77030 USA

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2008年 / 10卷 / 02期

关键词：

D O I：

10.1007/s11883-008-0024-0

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Inflammation plays a key role in the pathogenesis of atherosclerosis. Understanding the process of inflammation as it pertains to atherosclerosis has provided researchers with multiple opportunities to identify novel markers for use in cardiovascular disease management. This article discusses the inflammatory cascade as it pertains to atherosclerosis and some of the well-studied markers of inflammation. It also discusses the limitations of current risk stratification models and characteristics of a good biomarker.

引用

收藏

页码：164 / 170

页数：7

相关论文

共 59 条

[1] RELATION OF SERUM HOMOCYSTEINE AND LIPOPROTEIN(A) CONCENTRATIONS TO ATHEROSCLEROTIC DISEASE IN A PROSPECTIVE FINNISH POPULATION-BASED STUDY [J].

ALFTHAN, G ;

PEKKANEN, J ;

JAUHIAINEN, M ;

PITKANIEMI, J ;

KARVONEN, M ;

TUOMILEHTO, J ;

SALONEN, JT ;

EHNHOLM, C .

ATHEROSCLEROSIS, 1994, 106 (01) :9-19

[2]

*AM HEART ASS, 2002, 2002 HEART STROK STA

[3] Lipoprotein(a): A unique risk factor for cardiovascular disease [J].

Anuurad, Erdembileg ;

Boffa, Michael B. ;

Koschinsky, Marlys L. ;

Berglund, Lars .

CLINICS IN LABORATORY MEDICINE, 2006, 26 (04) :751-+

[4] Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes [J].

Baldus, S ;

Heeschen, C ;

Meinertz, T ;

Zeiher, AM ;

Eiserich, JP ;

Münzel, T ;

Simoons, ML ;

Hamm, CW .

CIRCULATION, 2003, 108 (12) :1440-1445

[5] Markers of inflammation and their clinical significance [J].

Ballantyne, C ;

Nambi, V .

ATHEROSCLEROSIS SUPPLEMENTS, 2005, 6 (02) :21-29

[6] Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study [J].

Ballantyne, CM ;

Hoogeveen, RC ;

Bang, H ;

Coresh, P ;

Folsom, AR ;

Chambless, LE ;

Myerson, M ;

Wu, KK ;

Sharrett, AR ;

Boerwinkle, E .

ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (21) :2479-2484

[7] Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study [J].

Ballantyne, CM ;

Hoogeveen, RC ;

Bang, H ;

Coresh, J ;

Folsom, AR ;

Heiss, G ;

Sharrett, AR .

CIRCULATION, 2004, 109 (07) :837-842

[8] A prospective evaluation of lipoprotein-associated phospholipase A2 levels and the risk of future cardiovascular events in women [J].

Blake, GJ ;

Dada, N ;

Fox, JC ;

Manson, JE ;

Ridker, PM .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 38 (05) :1302-1306

[9] Prognostic value of myeloperoxidase in patients with chest pain [J].

Brennan, M ;

Penn, MS ;

Van Lente, F ;

Nambi, V ;

Shishehbor, MH ;

Aviles, RJ ;

Goormastic, M ;

Pepoy, ML ;

McErlean, ES ;

Topol, EJ ;

Nissen, SE ;

Hazen, SL .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (17) :1595-1604

[10] Association of lipoprotein-associated phospholipase A2 levels with coronary artery disease risk factors, angiographic coronary artery disease, and major adverse events at follow-up [J].

Brilakis, ES ;

McConnell, JP ;

Lennon, RJ ;

Elesber, AA ;

Meyer, JG ;

Berger, PB .

EUROPEAN HEART JOURNAL, 2005, 26 (02) :137-144

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