Colorectal cancer in inflammatory bowel disease

被引:26
作者
Krok, KL [1 ]
Lichtenstein, GR [1 ]
机构
[1] Hosp Univ Penn, Ctr Inflammatory Bowel Dis, Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA
关键词
colorectal carcinoma; Crohn disease; ulcerative colitis; inflammatory bowel disease; colon cancer;
D O I
10.1097/00001574-200401000-00009
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Purpose of review Patients with inflammatory bowel disease, either Crohn disease or ulcerative colitis, are at an increased risk for developing colorectal carcinoma. Recent findings Surveillance colonoscopy, although never formally evaluated in a prospective controlled trial, is performed in an effort to reduce this risk. Novel methods of detecting dysplasia are constantly being evaluated, including chromoendoscopy and biomarkers of carcinoma, in an attempt to stratify patients who are at a higher risk of developing high-grade dysplasia or carcinoma. Summary Because of the potential impact on quality of life and life expectancy, an optimal strategy for reducing the risk of developing colorectal cancer in patients with inflammatory bowel disease needs to be defined.
引用
收藏
页码:43 / 48
页数:6
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