Rapid and efficient synthesis of poly-substituted quinolines assisted by p-toluene sulphonic acid under solvent-free conditions:: comparative study of microwave irradiation versus conventional heating

被引：146

作者：

Jia, CS

Zhang, Z

Tu, SJ

Wang, GW ^{[1
]}

机构：

[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

[3] Xuzhou Normal Univ, Dept Chem, Xuzhou 221116, Jiangsu, Peoples R China

[4] Xuzhou Normal Univ, Key Lab Biotechnol Med Plants, Xuzhou 221116, Jiangsu, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2006年 / 4卷 / 01期

关键词：

D O I：

10.1039/b513721g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rapid and efficient method for the preparation of various poly-substituted quinolines has been developed through the Friedlander condensation of 2-aminoarylketone or 2-aminoarylaldehyde with carbonyl compounds in the presence of p-toluene sulphonic acid, which was achieved by both microwave irradiation and conventional heating under solvent-free conditions.

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页码：104 / 110

页数：7

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