Are current diagnostic guidelines delaying early detection of dysglycemic states? Time for new approaches

被引：17

作者：

Bergman, Michael ^{[1
,2
]}

Dankner, Rachel ^{[3
,4
,5
]}

Roth, Jesse ^{[6
,7
,8
,9
]}

Narayan, K. M. Venkat ^{[10
]}

机构：

[1] NYU Diabet & Endocrine Associates, NYU Sch Med, New York, NY 10016 USA

[2] NYU Sch Med, Dept Med, Div Endocrinol, New York, NY USA

[3] Sheba Med Ctr, Gertner Inst Epidemiol & Hlth Policy Res, Unit Cardiovasc Epidemiol, Tel Hashomer, Israel

[4] Tel Aviv Univ, Sackler Fac Med, Sch Publ Hlth, Dept Epidemiol & Prevent Med, IL-69978 Tel Aviv, Israel

[5] Feinstein Inst Med Res, Manhasset, NY USA

[6] Feinstein Inst Med Res, Ctr Biomed Sci, Lab Diabet & Metab Disorders, Manhasset, NY USA

[7] Elmezzi Grad Sch Mol Med, Manhasset, NY USA

[8] Hofstra North Shore LIJ Sch Med, Hempstead, NY USA

[9] Yeshiva Univ, Albert Einstein Coll Med, New York, NY 10033 USA

[10] Emory Univ, Rollins Sch Publ Hlth, Hubert Dept Global Hlth, Ruth & OC Hubert Chair Global Hlth, Atlanta, GA 30322 USA

来源：

ENDOCRINE | 2013年 / 44卷 / 01期

关键词：

Prediabetes; Diabetes mellitus; Dysglycemia; Diabetes prevention; Impaired fasting glucose; Impaired glucose tolerance; HbA1c; 1,5-Anhydroglucitol; Adiponectin; Interleukin-1; beta; IL-1 receptor antagonist; HEALTH MANAGEMENT CENTER; FASTING GLUCOSE; BETA-CELL; TRAJECTORIES; INTERVENTION; PREVENTION; REDUCTION; HBA(1C);

D O I：

10.1007/s12020-013-9873-6

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Diagnosis of dysglycemic states is likely delayed as current diagnostic criteria apply absolute threshold values to a process that is continuous. The importance of this relates to forestalling opportunities for earlier diagnosis when prevention and reversibility are more likely to occur by preventing further beta cell dysfunction. Although the optimal method for earlier identification of individuals at risk remains uncertain, the paper suggests novel approaches.

引用

页码：66 / 69

页数：4

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