Gene silencing: Maintaining methylation patterns

被引:14
作者
Jacobsen, SE [1 ]
机构
[1] Univ Calif Los Angeles, Dept Cell Mol & Dev Biol, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/S0960-9822(99)80388-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent studies of an Arabidopsis gene family have shown that inverted repeats can be potent silencers of other identical sequences in the genome, causing them to become stably methylated at cytosine residues. From mutations affecting this process we are beginning to understand how methylation patterns are maintained.
引用
收藏
页码:R617 / R619
页数:3
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