Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

被引：2408

作者：

Nathan, David M. ^{[1
]}

Buse, John B. ^{[8
]}

Davidson, Mayer B. ^{[7
]}

Ferrannini, Ele ^{[6
]}

Holman, Rury R. ^{[5
]}

Sherwin, Robert ^{[3
,4
]}

Zinman, Bernard ^{[2
]}

机构：

[1] Massachusetts Gen Hosp, Ctr Diabet, Boston, MA 02114 USA

[2] Univ Toronto, Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada

[3] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06510 USA

[4] Yale Univ, Sch Med, Yale Ctr Clin Invest, New Haven, CT 06510 USA

[5] Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Diabet Trials Unit, Oxford, England

[6] Univ Pisa, Dept Internal Med, Pisa, Italy

[7] Charles R Drew Univ Med & Sci, Clin Ctr Res Excellence, Los Angeles, CA 90059 USA

[8] Univ N Carolina, Sch Med, Chapel Hill, NC USA

来源：

DIABETES CARE | 2009年 / 32卷 / 01期

关键词：

DIPEPTIDYL PEPTIDASE-4 INHIBITOR; INTENSIVE INSULIN THERAPY; IMPROVED GLYCEMIC CONTROL; MICROVASCULAR COMPLICATIONS; CARDIOVASCULAR EVENTS; COMBINATION THERAPY; EXENATIDE EXENDIN-4; BLOOD-GLUCOSE; DRUG-THERAPY; METFORMIN;

D O I：

10.2337/dc08-9025

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The consensus algorithm for the medical management of type 2 diabetes was published in August 2006 with the expectation that it would be updated, based on the availability of new interventions and new evidence to establish their clinical role. The authors continue to endorse the principles used to develop the algorithm and its major features. We are sensitive to the risks of changing the algorithm cavalierly or too frequently, without compelling new information. An update to the consensus algorithm published in January 2008 specifically addressed safety issues Surrounding the thiazolidinediones. In this revision, we focus on the new classes of medications that now have more clinical data and experience.

引用

页码：193 / 203

页数：11

共 92 条

[81]

SINGH S, DIABETES CARE, V30, P2248

[82] Long-term risk of cardiovascular events with rosiglitazone - A meta-analysis [J].

Singh, Sonal ;

Loke, Yoon K. ;

Furberg, Curt D. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (10) :1189-1195

[83] Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery [J].

Sjöström, L ;

Lindroos, AK ;

Peltonen, M ;

Torgerson, J ;

Bouchard, C ;

Carlsson, B ;

Dahlgren, S ;

Larsson, B ;

Narbro, K ;

Sjöström, CD ;

Sullivan, M ;

Wedel, H .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (26) :2683-2693

[84] Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study [J].

Stratton, IM ;

Adler, AI ;

Neil, HAW ;

Matthews, DR ;

Manley, SE ;

Cull, CA ;

Hadden, D ;

Turner, RC ;

Holman, RR .

BMJ-BRITISH MEDICAL JOURNAL, 2000, 321 (7258) :405-412

[85] Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) [J].

Turner, RC ;

Holman, RR ;

Stratton, IM ;

Cull, CA ;

Matthews, DR ;

Manley, SE ;

Frighi, V ;

Wright, D ;

Neil, A ;

Kohner, E ;

McElroy, H ;

Fox, C ;

Hadden, D .

LANCET, 1998, 352 (9131) :854-865

[86] Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) [J].

Turner, RC ;

Holman, RR ;

Cull, CA ;

Stratton, IM ;

Matthews, DR ;

Frighi, V ;

Manley, SE ;

Neil, A ;

McElroy, K ;

Wright, D ;

Kohner, E ;

Fox, C ;

Hadden, D ;

Mehta, Z ;

Smith, A ;

Nugent, Z ;

Peto, R ;

Adlel, AI ;

Mann, JI ;

Bassett, PA ;

Oakes, SF ;

Dornan, TL ;

Aldington, S ;

Lipinski, H ;

Collum, R ;

Harrison, K ;

MacIntyre, C ;

Skinner, S ;

Mortemore, A ;

Nelson, D ;

Cockley, S ;

Levien, S ;

Bodsworth, L ;

Willox, R ;

Biggs, T ;

Dove, S ;

Beattie, E ;

Gradwell, M ;

Staples, S ;

Lam, R ;

Taylor, F ;

Leung, L ;

Carter, RD ;

Brownlee, SM ;

Fisher, KE ;

Islam, K ;

Jelfs, R ;

Williams, PA ;

Williams, FA ;

Sutton, PJ .

LANCET, 1998, 352 (9131) :837-853

[87] Alpha-glucosidase inhibitors for type 2 diabetes mellitus (Review) - art. no. CD003639.pub2 [J].

Van de Laar, FA ;

Lucassen, PLBJ ;

Akkermans, RP ;

Van de Lisdonk, EH ;

Rutten, GEHM ;

Van Weel, C .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2005, (02)

[88] Self-monitoring of blood glucose in patients with type 2 diabetes who are not using insulin: A systematic review [J].

Welschen, LMC ;

Heine, RJ ;

Bloemendal, E ;

Stalman, WAB ;

Nijpels, G ;

Bouter, LM ;

Dekker, JM .

DIABETES CARE, 2005, 28 (06) :1510-1517

[89] Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes:: a multicentre randomised parallel-group trial [J].

Weng, Jianping ;

Li, Yanbing ;

Xu, Wen ;

Shi, Lixin ;

Zhang, Qiao ;

Zhu, Dalong ;

Hu, Yun ;

Zhou, Zhiguang ;

Yan, Xiang ;

Tian, Haoming ;

Ran, Xingwu ;

Luo, Zuojie ;

Xian, Jing ;

Yan, Li ;

Li, Fangping ;

Zeng, Longyi ;

Chen, Yanming ;

Yang, Liyong ;

Yan, Sunjie ;

Liu, Juan ;

Li, Ming ;

Fu, Zuzhi ;

Cheng, Hua .

LANCET, 2008, 371 (9626) :1753-1760

[90] Comparison of bedtime insulin regimens in patients with type 2 diabetes mellitus -: A randomized, controlled trial [J].

Yki-Järvinen, H ;

Ryysy, L ;

Nikkilä, K ;

Tulokas, T ;

Vanamo, R ;

Heikkilä, M .

ANNALS OF INTERNAL MEDICINE, 1999, 130 (05) :389-+

← 1 2 3 4 5 6 7 8 9 10 →