Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord

被引：121

作者：

Mennan, Claire ^{[1
,2
]}

Wright, Karina ^{[1
,2
]}

Bhattacharjee, Atanu ^{[3
]}

Balain, Birender ^{[3
]}

Richardson, James ^{[3
]}

Roberts, Sally ^{[1
,2
]}

机构：

[1] Keele Univ, Robert Jones & Agnes Hunt Orthopaed Hosp NHS Fdn, Oswestry SY10 7AG, Shrops, England

[2] Keele Univ, ISTM, Oswestry SY10 7AG, Shrops, England

[3] Robert Jones & Agnes Hunt Orthopaed Hosp NHS Fdn, Inst Orthopaed, Oswestry SY10 7AG, Shrops, England

来源：

BIOMED RESEARCH INTERNATIONAL | 2013年 / 2013卷

关键词：

BONE-MARROW; TRANSPLANTATION; THERAPY;

D O I：

10.1155/2013/916136

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Umbilical cords as a source of stemcells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton's jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics.

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页数：8

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