Association of cagA and vacA genotypes of Helicobacter pylori with gastric diseases in Estonia

被引：35

作者：

Andreson, H

Loivukene, K

Sillakivi, T

Maaroos, HI

Ustav, M

Peetsalu, A

Mikelsaar, M

机构：

[1] Univ Tartu, Dept Microbiol, EE-50411 Tartu, Estonia

[2] Univ Tartu, Dept Surg, EE-50411 Tartu, Estonia

[3] Univ Tartu, Dept Polyclin & Family Med, EE-50411 Tartu, Estonia

[4] Univ Tartu, Inst Mol & Cell Biol, EE-50411 Tartu, Estonia

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 01期

关键词：

D O I：

10.1128/JCM.40.1.298-300.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Gastric biopsy specimens from 156 adult patients from southern Estonia suffering from chronic gastritis, peptic ulcer disease, and perforated peptic ulcer were analyzed by PCR. The cagA gene was evenly distributed throughout 87% of the specimens from the patients with the different gastric diseases. The presence of the cagA gene correlated with that of vacA signal sequence type s1a (99%). However, no clear differences were found in the distribution of cagA and vacA genotypes among patients in Estonia with severe perforated peptic ulcer, uncomplicated peptic ulcer, or chronic gastritis.

引用

页码：298 / 300

页数：3

共 30 条

[1] MOSAICISM IN VACUOLATING CYTOTOXIN ALLELES OF HELICOBACTER-PYLORI - ASSOCIATION OF SPECIFIC VACA TYPES WITH CYTOTOXIN PRODUCTION AND PEPTIC-ULCERATION [J].