Proton transport mechanism of bacteriorhodopsin as revealed by site-specific mutagenesis and protein sequence variability

被引：27

作者：

Brown, LS ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Physiol & Biophys, Irvine, CA 92697 USA

来源：

BIOCHEMISTRY-MOSCOW | 2001年 / 66卷 / 11期

关键词：

bacteriorhodopsin; halobacteria; mutations; photocycle; proton transport; conserved residues;

D O I：

10.1023/A:1013131318620

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A large share of the current ideas about the mechanism of proton transport by bacteriorhodopsin has emerged from studies of site-specific mutants. This review is an attempt to check some of these ideas against the natural variability in the primary structure of the protein.

引用

页码：1249 / 1255

页数：7

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