Evaluation of the use of RT-PCR for the early diagnosis of dengue fever

被引：16

作者：

Grobusch, MP

Niedrig, M

Göbels, K

Klipstein-Grobusch, K

Teichmann, D

机构：

[1] Humboldt Univ, Med Clin, Dept Infect Dis, Charite, D-1086 Berlin, Germany

[2] German Inst Human Nutr, DIfE, Nuthetal, Germany

[3] Robert Koch Inst, D-1000 Berlin, Germany

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2006年 / 12卷 / 04期

关键词：

dengue fever; diagnosis; RT-PCR; sampling time; sensitivity;

D O I：

10.1111/j.1469-0691.2006.01353.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

RT-PCR was used to diagnose dengue virus infections confirmed serologically in 26 returning travellers. RT-PCR was positive for three (75%) of four samples taken on or before day 3 of the illness, for 15 (78.9%) of 19 samples taken between days 4 and 7, and for none of three samples tested on or after day 8 (p 0.0337). When applied early, RT-PCR seems to be a useful tool for the diagnosis of dengue fever.

引用

页码：395 / 397

页数：3

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