Chemiluminescence flow-injection determination of furosemide based on a rhodamine 6G sensitized cerium(IV) method

被引：50

作者：

Rao, Y

Zhang, XR ^{[1
]}

Luo, GA

Baeyens, WRG

机构：

[1] Tsing Hua Univ, Dept Chem, Beijing 100084, Peoples R China

[2] Jiangxi Tradit Chinese Med Coll, Dept Pharm, Nanchang 330006, Peoples R China

[3] State Univ Ghent, Fac Pharmaceut Sci, B-9000 Ghent, Belgium

来源：

ANALYTICA CHIMICA ACTA | 1999年 / 396卷 / 2-3期

关键词：

chemiluminescence; flow-injection analysis; furosemide;

D O I：

10.1016/S0003-2670(99)00425-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A flow-injection method is described for the determination of furosemide in the range 1.0-50.0 mu mol l(-1), with a detection Limit of 0.22 mu mol l(-1) and a relative standard deviation of 2.1% at 10 mu mol l(-1) (n = 10). The method is based on the chemiluminescence reaction of furosemide with cerium (IV) in sulphuric acid, sensitized by rhodamine 6G. By applying the method to tablets and injection solutions, it was found that the present method is relatively free from interference and tolerable to turbid solutions. (C)1999 Elsevier Science B.V. All rights reserved.

引用

页码：273 / 277

页数：5

共 26 条

[1] Determination of piretanide and furosemide in pharmaceuticals and human urine by high-performance liquid chromatography with amperometric detection [J].