Non-ST segment elevation acute coronary syndromes: A simplified risk-oriented algorithm

被引:14
作者
Fitchett, David H.
Borgundvaag, Bjug
Cantor, Warren
Cohen, Eric
Dhingra, Sanjay
Fremes, Stephen
Gupta, Milan
Heffernan, Michael
Kertland, Heather
Husain, Mansoor
Langer, Anatoly
Letovsky, Eric
Goodman, Shaun G.
机构
[1] St Michaels Hosp, Div Cardiol, Terrence Donnelly Heart Ctr, Toronto, ON M5B 1W8, Canada
[2] Canadian Heart Res Ctr, Toronto, ON, Canada
[3] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada
[4] South Lake Hosp, Newmarket, ON, Canada
[5] Sunnybrook & Womens Coll Hosp, Toronto, ON, Canada
[6] Scarborough Gen Hosp, Scarborough, ON, Canada
[7] William Osler Hlth Ctr, Brampton, ON, Canada
[8] Oakville Trafalgar Hosp, Oakville, ON, Canada
[9] Univ Hlth Network, Toronto, ON, Canada
[10] Credit Valley Hosp, Mississauga, ON, Canada
关键词
anticoagulants; coronary disease; myocardial infarction; platelet aggregation inhibitors; thrombosis;
D O I
10.1016/S0828-282X(06)70935-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Non-ST segment elevation acute coronary syndromes (NSTE ACS) include a clinical spectrum that ranges from Unstable angina to NSTE myocardial infarction. Management goals aim to prevent recurrent ACS and improve long,term outcomes by choosing a treatment strategy according to an estimate of the risk of an adverse outcome. Recent registry data suggest that patients with NSTE ACS frequently do not receive recommended treatment, and that risk stratification is not used to determine either the choice of treatment or the speed of access to coronary angiography. The present article evaluates the evidence for recommended treatment Using information from recent trials and guidelines published by the major cardiac organizations in Europe and North America. Using this information, a multidisciplinary group developed a simplified algorithm that uses risk stratification to select an optimal early management strategy. Long-term outcomes are improved by a multifaceted vascular protection strategy that is initiated at the time of hospitalization for NSTE ACS.
引用
收藏
页码:663 / 677
页数:15
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