Enantiospecific adsorption of cysteine at chiral kink sites on Au(110)-(1x2)

Enantiospecific adsorption of cysteine molecules onto chiral kink sites on the Au(110)-(1×2) surface was observed by scanning tunneling microscopy. l- and d-cysteine dimers were found to adopt distinctly different adsorption geometries at S kinks, which can be understood from the need to reach specific, optimum molecule-substrate interaction points. Extended, homochiral domains of l/d-cysteine were furthermore observed to grow preferentially from R/S kinks. The results constitute the first direct, microscopic observation of enantiospecific molecular interaction with chiral sites on a metal single-crystal surface. Copyright © 2006 American Chemical Society.