A versatile and efficient ligand for copper-catalyzed formation of C-N, C-o, and P-C bonds: Pyrrolidine-2-phosphonic acid phenyl monoester

被引：373

作者：

Rao, HH

Jin, Y

Fu, H ^{[1
]}

Jiang, YY

Zhao, YF

机构：

[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China

[2] Tsing Hua Univ, Grad Sch Shenzhen, Key Lab Chem Biol Guangdong Prov, Shenzhen 518057, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2006年 / 12卷 / 13期

关键词：

arylation; copper; cross-coupling; homogeneous catalysis; N; O ligands;

D O I：

10.1002/chem.200501473

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new and readily available bidentate ligand, namely, pyrrolidine-2-phosphonic acid phenyl monoester (PPAPM), has been developed for the coppercatalyzed formation of C-N, C-O, and P-C bonds, and various N-, O-, and P-arylation products were synthesized in good to excellent yields by using the Cul/ PPAPM catalyst system. Addition of the PPAPM ligand greatly increases the reactivity of the copper catalyst, and the resulting versatile and efficient catalyst system is of widespread and practical application in cross-coupling reactions.

引用

页码：3636 / 3646

页数：11

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