Plasma baclofen levels in children receiving continuous intrathecal baclofen infusion

被引:26
作者
Albright, AL [1 ]
Shultz, BL [1 ]
机构
[1] Childrens Hosp Pittsburgh, Dept Neurosurg, Pittsburgh, PA 15213 USA
关键词
D O I
10.1177/088307389901400611
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
To determine the plasma baclofen concentrations of children undergoing continuous intrathecal baclofen infusion for treatment of cerebral spasticity, we assayed plasma samples from six children, 8 to 18 years of age, who were receiving intrathecal baclofen at constant rates of 77 to 400 mu g/day. Plasma levels were at or below the limit of quantification (10 ng/mL) in all patients.
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页码:408 / 409
页数:2
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