Measles vaccination effectiveness among children under 5 years of age in Kampala, Uganda

被引：22

作者：

Mupere, Ezekiel

Karamagi, Charles

Zirembuzi, George

Grabowsky, Mark

de Swart, Rik L.

Nanyunja, Miriam

Mayanja, Harriet

机构：

[1] Makerere Univ, Dept Paediat & Child Hlth, Fac Med, Kampala, Uganda

[2] Mulago Hosp, Dept Paediat & Child Hlth, Kampala, Uganda

[3] WHO Country Off, Kampala, Uganda

[4] Erasmus MC, Dept Virol, Rotterdam, Netherlands

[5] Uganda Virus Res Inst, Minist Hlth, Entebbe, Uganda

[6] Makerere Univ, Dept Med, Kampala, Uganda

来源：

VACCINE | 2006年 / 24卷 / 19期

关键词：

measles vaccination effectiveness; attack rates; filter paper blood samples;

D O I：

10.1016/j.vaccine.2006.02.038

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Measles control remains a great challenge in Uganda. We conducted a prospective study among household contacts aged 9-59 months to assess measles vaccination effectiveness. Index cases were measles patients seen in Kampala hospitals in 1999, Measles was diagnosed in 37/43 (86%) of unvaccinated and in 33/145 (23%) of vaccinated exposed contacts, respectively. Vaccination effectiveness was 74% (95% Cl; 64-81), which was lower than expected. This may indicate the need for strengthening of the cold chain and/or introduction of a second opportunity for measles vaccination, either as part of the routine immunization program or in the form of supplementary immunization activities. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：4111 / 4115

页数：5

共 30 条

[1] VACCINATED CHILDREN GET MILDER MEASLES INFECTION - A COMMUNITY STUDY FROM GUINEA-BISSAU [J].