OPM: Orientations of proteins in membranes database

被引:949
作者
Lomize, MA
Lomize, AL [1 ]
Pogozheva, ID
Mosberg, HI
机构
[1] Univ Michigan, Coll Pharm, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Coll Literature Sci & Arts, Ann Arbor, MI 48109 USA
关键词
D O I
10.1093/bioinformatics/btk023
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The Orientations of Proteins in Membranes (OPM) database provides a collection of transmembrane, monotopic and peripheral proteins from the Protein Data Bank whose spatial arrangements in the lipid bilayer have been calculated theoretically and compared with experimental data. The database allows analysis, sorting and searching of membrane proteins based on their structural classification, species, destination membrane, numbers of transmembrane segments and subunits, numbers of secondary structures and the calculated hydrophobic thickness or tilt angle with respect to the bilayer normal. All coordinate files with the calculated membrane boundaries are available for downloading.
引用
收藏
页码:623 / 625
页数:3
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