Dichlorodiaportin, diaportinol, and diaportinic acid:: Three novel isocoumarins from Penicillium nalgiovense

被引：89

作者：

Larsen, TO ^{[1
]}

Breinholt, J

机构：

[1] Tech Univ Denmark, Dept Biotechnol, Mycol Grp, DK-2800 Lyngby, Denmark

[2] Novo Nordisk AS, DK-2760 Malov, Denmark

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 08期

关键词：

D O I：

10.1021/np990066b

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three novel isocoumarin (or isochromen) metabolites, dichlorodiaportin [3-(3,3-dichloro-2-hydroxy-propyl)-8-hydroxy-6-methoxy-isochromen-1-one] (1), diaportinol [3-(2,3-dihydroxy-propyl)-8-hydroxy-6-methoxyisochromen-1-one] (2), and diaportinic acid [2-hydroxy-3 -(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl)-propanoic acid] (3), were isolated from the cultures of Penicillium nalgiovense along with citreoisocoumarin (4) and 6-methyl-citreoisocoumarin (5). Their structures were elucidated by spectroscopic methods including UV, MS, and NMR.

引用

页码：1182 / 1184

页数：3

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