Common mechanisms of autoimmune diseases (the autoimmune tautology)

被引：119

作者：

Anaya, Juan-Manuel ^{[1
]}

机构：

[1] Univ Rosario, Ctr Autoimmune Dis Res CREA, Sch Med & Hlth Sci, Bogota, Colombia

来源：

AUTOIMMUNITY REVIEWS | 2012年 / 11卷 / 11期

关键词：

Autoimmune tautology; Autoimmune diseases; Polyautoimmunity; Familial autoimmunity; Genetics; Autoantibodies; SYSTEMIC-LUPUS-ERYTHEMATOSUS; AMERINDIAN ANCESTRY; INFLAMMATION; GENETICS; VIRUS; RISK;

D O I：

10.1016/j.autrev.2012.02.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

The fact that autoimmune diseases share subphenotypes, physiopathological mechanisms and genetic factors has been called autoimmune tautology, and indicates that they have a common origin. The autoimmune phenotypes vary depending on the target cell and the affected organ, gender, ancestry, trigger factors and age at onset. Ten shared characteristics supporting this logical theory are herein reviewed. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：781 / 784

页数：4

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