Apoptosis - Akt is more than just a Bad kinase

被引：274

作者：

Khwaja, A ^{[1
]}

机构：

[1] UCL, Sch Med, Dept Haematol, London WC1E 6HX, England

来源：

NATURE | 1999年 / 401卷 / 6748期

关键词：

D O I：

10.1038/43354

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

The decision for a cell to live or die depends on changes in its external environment, which are integrated into a survival response by signal-transduction mechanisms. A protein called Akt is an important component of pro-survival signalling pathways, and a sheaf of papers now tells us more about how it acts. In particular, these studies show that Akt alters the activity of factors that regulate gene transcription.

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页码：33 / 34

页数：2

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