In vitro activities of the des-fluoro(6) quinolone BMS-284756 against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections

被引：17

作者：

Goldstein, EJC

Citron, DM

Merriam, CV

Warren, YA

Tyrrell, KL

Fernandez, H

机构：

[1] Univ Calif Los Angeles, Med Ctr, RM Alden Res Lab, Santa Monica, CA 90404 USA

[2] Univ Calif Los Angeles, Sch Med, Los Angeles, CA 90073 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 03期

关键词：

D O I：

10.1128/AAC.46.3.866-870.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

BMS-284756, a new des-fluoro(6) quinolone, was very active against 240 aerobic and 180 anaerobic isolates from bite victims. It inhibited 403 of 420 (96%) isolates, including those of Maraxella spp., CDC group EF-4, and Eikenella corrodens at less than or equal to2 mug/ml and those of all Pasteurella spp. and Bergeyella zoohelcum at less than or equal to0.015 mug/ml. Fusobacterium russii and 6 of 11 Fusobacterium nucleatum isolates of animal bite origin were resistant, but isolates of human bite origin were susceptible, which suggests that they were of a different subspecies.

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收藏

页码：866 / 870

页数：5

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