DNA repair: Polymerases for passing lesions

被引:24
作者
Bridges, BA [1 ]
机构
[1] Univ Sussex, MRC, Cell Mutat Unit, Brighton BN1 9RR, E Sussex, England
关键词
D O I
10.1016/S0960-9822(99)80299-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Replicative DNA polymerases generally cannot pass lesions in the template strand. Now there is accumulating evidence for the widespread existence of a separate class of DNA polymerases that can carry out translesion synthesis in both mutagenic and error-free ways.
引用
收藏
页码:R475 / R477
页数:3
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