Reduction of α-aryloxy carbonyl compounds with samarium(II) iodide.: A new traceless linker for the solid phase synthesis of carbonyl compounds

被引:32
作者
McKerlie, F
Procter, DJ
Wynne, G
机构
[1] Univ Glasgow, Dept Chem, Glasgow G12 8QQ, Lanark, Scotland
[2] OSI Pharmaceut Uk Ltd, Oxford OX4 6LT, England
关键词
D O I
10.1039/b200365c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new linker for the solid phase synthesis of functionalised carbonyl compounds which is cleaved under mild, neutral conditions using samarium(II) iodide has been developed; the manipulation of an immobilised gamma-butyrolactone has been carried out to illustrate the utility of the linker.
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页码:584 / 585
页数:2
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