Standards for systems biology

被引:86
作者
Brazma, Alvis
Krestyaninova, Maria
Sarkans, Ugis
机构
[1] European Bioinformatics Institute, EMBL-EBI, Wellcome Trust Genome Campus
关键词
D O I
10.1038/nrg1922
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
High-throughput technologies are generating large amounts of complex data that have to be stored in databases, communicated to various data analysis tools and interpreted by scientists. Data representation and communication standards are needed to implement these steps efficiently. Here we give a classification of various standards related to systems biology and discuss various aspects of standardization in life sciences in general. Why are some standards more successful than others, what are the prerequisites for a standard to succeed and what are the possible pitfalls?
引用
收藏
页码:593 / 605
页数:13
相关论文
共 49 条
  • [1] [Anonymous], 2002, Nature, V419, P323
  • [2] Gene Ontology: tool for the unification of biology
    Ashburner, M
    Ball, CA
    Blake, JA
    Botstein, D
    Butler, H
    Cherry, JM
    Davis, AP
    Dolinski, K
    Dwight, SS
    Eppig, JT
    Harris, MA
    Hill, DP
    Issel-Tarver, L
    Kasarskis, A
    Lewis, S
    Matese, JC
    Richardson, JE
    Ringwald, M
    Rubin, GM
    Sherlock, G
    [J]. NATURE GENETICS, 2000, 25 (01) : 25 - 29
  • [3] Submission of microarray data to public repositories
    Ball, CA
    Brazma, A
    Causton, H
    Chervitz, S
    Edgar, R
    Hingamp, P
    Matese, JC
    Parkinson, H
    Quackenbush, J
    Ringwald, M
    Sansone, SA
    Sherlock, G
    Spellman, P
    Stoeckert, C
    Tateno, Y
    Taylor, R
    White, J
    Winegarden, N
    [J]. PLOS BIOLOGY, 2004, 2 (09) : 1276 - 1277
  • [4] An ontology for cell types
    Bard, J
    Rhee, SY
    Ashburner, M
    [J]. GENOME BIOLOGY, 2005, 6 (02)
  • [5] Ontologies in biology: Design, applications and future challenges
    Bard, JBL
    Rhee, SY
    [J]. NATURE REVIEWS GENETICS, 2004, 5 (03) : 213 - 222
  • [6] Barrett T, 2005, NUCLEIC ACIDS RES, V33, pD562
  • [7] Minimum information about a microarray experiment (MIAME) - toward standards for microarray data
    Brazma, A
    Hingamp, P
    Quackenbush, J
    Sherlock, G
    Spellman, P
    Stoeckert, C
    Aach, J
    Ansorge, W
    Ball, CA
    Causton, HC
    Gaasterland, T
    Glenisson, P
    Holstege, FCP
    Kim, IF
    Markowitz, V
    Matese, JC
    Parkinson, H
    Robinson, A
    Sarkans, U
    Schulze-Kremer, S
    Stewart, J
    Taylor, R
    Vilo, J
    Vingron, M
    [J]. NATURE GENETICS, 2001, 29 (04) : 365 - 371
  • [8] ArrayExpress - a public repository for microarray gene expression data at the EBI
    Brazma, A
    Parkinson, H
    Sarkans, U
    Shojatalab, M
    Vilo, J
    Abeygunawardena, N
    Holloway, E
    Kapushesky, M
    Kemmeren, P
    Lara, GG
    Oezcimen, A
    Rocca-Serra, P
    Sansone, SA
    [J]. NUCLEIC ACIDS RESEARCH, 2003, 31 (01) : 68 - 71
  • [9] One-stop shop for microarray data - Is a universal, public DNA-microarray database a realistic goal?
    Brazma, A
    Robinson, A
    Cameron, G
    Ashburner, M
    [J]. NATURE, 2000, 403 (6771) : 699 - 700
  • [10] On the importance of standardisation in life sciences
    Brazma, A
    [J]. BIOINFORMATICS, 2001, 17 (02) : 113 - 114