Microfluidic devices for DNA analysis

被引：39

作者：

Ehrlich, DJ

Matsudaira, P

机构：

[1] Whitehead Inst Biomed Res, Cambridge, MA 02142 USA

[2] MIT, Cambridge, MA 02142 USA

来源：

TRENDS IN BIOTECHNOLOGY | 1999年 / 17卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0167-7799(99)01310-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Microfabricated electrophoresis devices allow us to perform short-tandem-repeat genotyping assays in under 2 min and sequence single-stranded DNA in under 15 min. This is 10-100 times faster than standard slab-gel and capillary systems. The microdevice format is the natural extension of 100 years of gradual improvements to electrophoresis but operates in an almost-perfect way, limited only by the sieving medium.

引用

收藏

页码：315 / 319

页数：5

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