CAPILLARY ARRAY ELECTROPHORESIS - AN APPROACH TO HIGH-SPEED, HIGH-THROUGHPUT DNA SEQUENCING

被引：181

作者：

MATHIES, RA

HUANG, XC

机构：

来源：

NATURE | 1992年 / 359卷 / 6391期

关键词：

D O I：

10.1038/359167a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The speed and throughput of DNA sequencing can be increased by performing sequencing separations on arrays of microcapillaries followed by detection with a laser-excited, confocal-fluorescence scanner.

引用

页码：167 / 169

页数：3

共 18 条

[1] SEPARATION AND ANALYSIS OF DNA-SEQUENCE REACTION-PRODUCTS BY CAPILLARY GEL-ELECTROPHORESIS
COHEN, AS
NAJARIAN, DR
KARGER, BL
[J]. JOURNAL OF CHROMATOGRAPHY, 1990, 516 (01): : 49 - 60
[2] A STABLE DOUBLE-STRANDED DNA ETHIDIUM HOMODIMER COMPLEX - APPLICATION TO PICOGRAM FLUORESCENCE DETECTION OF DNA IN AGAROSE GELS
GLAZER, AN
PECK, K
MATHIES, RA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (10) : 3851 - 3855
[3] SEPARATION OF DNA RESTRICTION FRAGMENTS BY HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS WITH LOW AND ZERO CROSS-LINKED POLYACRYLAMIDE USING CONTINUOUS AND PULSED ELECTRIC-FIELDS
HEIGER, DN
COHEN, AS
KARGER, BL
[J]. JOURNAL OF CHROMATOGRAPHY, 1990, 516 (01): : 33 - 48
[4] DNA SEQUENCING USING CAPILLARY ARRAY ELECTROPHORESIS
HUANG, XHC
QUESADA, MA
MATHIES, RA
[J]. ANALYTICAL CHEMISTRY, 1992, 64 (18) : 2149 - 2154
[5] HUANGXC, 1992, ANAL CHEM, V64, P967
[6] LARGE-SCALE AND AUTOMATED DNA-SEQUENCE DETERMINATION
HUNKAPILLER, T
KAISER, RJ
KOOP, BF
HOOD, L
[J]. SCIENCE, 1991, 254 (5028) : 59 - 67
[7] HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS
KARGER, BL
[J]. NATURE, 1989, 339 (6226) : 641 - 642
[8] HIGH-SPEED AUTOMATED DNA SEQUENCING IN ULTRATHIN SLAB GELS
KOSTICHKA, AJ
MARCHBANKS, ML
BRUMLEY, RL
DROSSMAN, H
SMITH, LM
[J]. BIO-TECHNOLOGY, 1992, 10 (01): : 78 - 81
[9] HIGH-SPEED DNA SEQUENCING BY CAPILLARY ELECTROPHORESIS
LUCKEY, JA
DROSSMAN, H
KOSTICHKA, AJ
MEAD, DA
DCUNHA, J
NORRIS, TB
SMITH, LM
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (15) : 4417 - 4421
[10] PENTONEY SL, 1992, MAY P CLEO QELS AN, P94

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