Molecular features and functional constraints in the evolution of the mammalian X chromosome

被引：7

作者：

Khil, PR ^{[1
]}

Camerini-Otero, RD ^{[1
]}

机构：

[1] NIDDK, Genet & Biochem Branch, NIH, Bethesda, MD 20892 USA

来源：

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY | 2005年 / 40卷 / 06期

关键词：

retrotransposition; sex determination; meiotic sex chomosome inactivation; MSCI; epigenetics; sexual antagonism; sex-biased genes;

D O I：

10.1080/10409230500356703

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent advances in genomic sequencing of multiple organisms have fostered significant advances in our understanding of the evolution of the sex chromosomes. The integration of this newly available sequence information with functional data has facilitated a considerable refinement of our conceptual framework of the forces driving this evolution. Here we address multiple functional constraints that were encountered in the evolution of the X chromosome and the impact that this evolutionary history has had on its modern behavior.

引用

页码：313 / 330

页数：18

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