Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular strand-replacement polymerization on magnetic nanoparticles

被引：31

作者：

Gao, Fenglei ^{[1
]}

Zhu, Zhu ^{[1
]}

Lei, Jianping ^{[1
]}

Ju, Huangxian ^{[1
]}

机构：

[1] Nanjing Univ, Dept Chem, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 86期

基金：

中国国家自然科学基金;

关键词：

NUCLEIC-ACIDS; PATHOGEN DNA; SCATTERING; HYBRIDIZATION; MICROARRAYS;

D O I：

10.1039/c2cc35203f

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

A novel strategy of dual signal amplification was developed using circular strand-replacement DNA polymerization with a molecular beacon as a switch and silver enhancement on magnetic nanoparticles for the specific Raman spectroscopic detection of DNA down to the sub-picomolar level.

引用

收藏

页码：10603 / 10605

页数：3

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