Cortex Shatters the Glass Ceiling

被引：7

作者：

Au, Edmund ^{[1
]}

Fishell, Gord ^{[1
]}

机构：

[1] NYU, Langone Med Ctr, Dept Cell Biol, Smilow Neurosci Program, New York, NY 10016 USA

来源：

CELL STEM CELL | 2008年 / 3卷 / 05期

关键词：

D O I：

10.1016/j.stem.2008.10.013

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Recreating developmental structures in vitro has been a primary challenge for stem cell biologists. Recent studies in Cell Stem Cell (Eiraku et al., 2008) and Nature (Gaspard et al., 2008) demonstrate that embryonic stem cells can recapitulate early cortical development, enabling them to generate specific cortical subtypes.

引用

页码：472 / 474

页数：3

共 11 条

[1] Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals [J].

Eiraku, Mototsugu ;

Watanabe, Kiichi ;

Matsuo-Takasaki, Marni ;

Kawada, Masako ;

Yonemura, Shigenobu ;

Matsumura, Michiru ;

Wataya, Takafumi ;

Nishiyama, Ayaka ;

Muguruma, Keiko ;

Sasail, Yoshiki .

CELL STEM CELL, 2008, 3 (05) :519-532

[2] An intrinsic mechanism of corticogenesis from embryonic stem cells [J].

Gaspard, Nicolas ;

Bouschet, Tristan ;

Hourez, Raphael ;

Dimidschstein, Jordane ;

Naeije, Gilles ;

van den Ameele, Jelle ;

Espuny-Camacho, Ira ;

Herpoel, Adele ;

Passante, Lara ;

Schiffmann, Serge N. ;

Gaillard, Afsaneh ;

Vanderhaeghen, Pierre .

NATURE, 2008, 455 (7211) :351-U10

[3] Differential modulation of proliferation in the neocortical ventricular and subventricular zones [J].

Haydar, TF ;

Wang, F ;

Schwartz, ML ;

Rakic, P .

JOURNAL OF NEUROSCIENCE, 2000, 20 (15) :5764-5774

[4] Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells [J].

Lee, SH ;

Lumelsky, N ;

Studer, L ;

Auerbach, JM ;

McKay, RD .

NATURE BIOTECHNOLOGY, 2000, 18 (06) :675-679

[5] The determination of projection neuron identity in the developing cerebral cortex [J].

Leone, Dino P. ;

Srinivasan, Karpagam ;

Chen, Bin ;

Alcamo, Elizabeth ;

McConnell, Susan K. .

CURRENT OPINION IN NEUROBIOLOGY, 2008, 18 (01) :28-35

[6] Differential Notch signalling distinguishes neural stem cells from intermediate progenitors [J].

Mizutani, Ken-ichi ;

Yoon, Keejung ;

Dang, Louis ;

Tokunaga, Akinori ;

Gaiano, Nicholas .

NATURE, 2007, 449 (7160) :351-+

[7] Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells [J].

Osakada, Fumitaka ;

Ikeda, Hanako ;

Mandai, Michiko ;

Wataya, Takafumi ;

Watanabe, Kiichi ;

Yoshimura, Nagahisa ;

Akaike, Akiori ;

Sasai, Yoshiki ;

Takahashi, Masayo .

NATURE BIOTECHNOLOGY, 2008, 26 (02) :215-224

[8] The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells [J].

Shen, Qin ;

Wang, Yue ;

Dimos, John T. ;

Fasano, Christopher A. ;

Phoenix, Timothy N. ;

Lemischka, Ihor R. ;

Ivanova, Natalia B. ;

Stifani, Stefano ;

Morrisey, Edward E. ;

Temple, Sally .

NATURE NEUROSCIENCE, 2006, 9 (06) :743-751

[9]

Tarabykin V, 2001, DEVELOPMENT, V128, P1983

[10] Directed differentiation of telencephalic precursors from embryonic stem cells [J].

Watanabe, K ;

Kamiya, D ;

Nishiyama, A ;

Katayama, T ;

Nozaki, S ;

Kawasaki, H ;

Watanabe, Y ;

Mizuseki, K ;

Sasai, Y .

NATURE NEUROSCIENCE, 2005, 8 (03) :288-296

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