A catalytic approach to (R)-(+)-muscopyridine with integrated "self-clearance"

被引：205

作者：

Fürstner, A ^{[1
]}

Leitner, A ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 03期

关键词：

cross-coupling; iron; macrocycles; metathesis; ruthenium;

D O I：

10.1002/anie.200390103

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The integration of various metal-catalyzed reactions into a one-pot processes opens an unprecedentedly short and efficient route to the odoriferous alkaloid (R)-(+)-muscopyridine. Importantly, it is shown how metathesis can be used for a most convenient self-clearance" of a product mixture (see scheme; OTf= CF3SO3)."

引用

页码：308 / +

页数：5

共 54 条

[1] [Anonymous], 2002, ANGEW CHEM
[2] PYRYLIUM SALTS OBTAINED BY DIACYLATION OF OLEFINS .8. INTRAMOLECULAR DIACYLATION
BALABAN, AT
NENITZESCO, CD
GAVAT, M
[J]. TETRAHEDRON, 1962, 18 (OCT) : 1079 - &
[3] THE STRUCTURE AND SYNTHESIS OF MUSCOPYRIDINE
BIEMANN, K
BUCHI, G
WALKER, BH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (20) : 5558 - 5564
[4] Cahiez G, 1998, SYNTHESIS-STUTTGART, P1199
[5] Corey E.J., 1989, The Logic of Chemical Synthesis
[6] DUBS P, 1976, J CHEM SOC CHEM COMM, P1021
[7] SYNTHESIS OF (2S,4S,6S)-2-AMINO-6-HYDROXY-4-METHYL-8-OXODECANOIC ACID AND (4S,E)-4-METHYLHEX-2-ENOIC ACID CONSTITUENTS OF LEUCINOSTATINES
ELHADRAMI, M
LAVERGNE, JP
VIALLEFONT, P
ITTO, MYA
HASNAOUI, A
[J]. TETRAHEDRON LETTERS, 1991, 32 (32) : 3985 - 3988
[8] Fgrstner A., 1999, U. S. Patent, Patent No. [5,936,100, 5936100]
[9] Fürstner A, 2002, ANGEW CHEM INT EDIT, V41, P609
[10] Iron-catalyzed cross-coupling reactions
Fürstner, A
Leitner, A
Méndez, M
Krause, H
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (46) : 13856 - 13863

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