Addition reactions of cyclic s-trans-enaminones with Grignard reagents.

被引：9

作者：

Shawe, TT

Hansen, DB

Peet, KA

Prokopowicz, AS

Robinson, PM

Cannon, A

Dougherty, KE

Ross, AA

Landino, LM

机构：

[1] Department of Chemistry, Bucknell University, Lewisburg

来源：

TETRAHEDRON | 1997年 / 53卷 / 05期

关键词：

D O I：

10.1016/S0040-4020(96)01133-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of Grignard reagents to s-trans-enaminones derived from 1,3-cycloalkanediones are described. In dichloromethane, addition of phenylmagnesium bromide gave 3-phenyl substituted cycloalkenones. Alkylmagnesium halides underwent multiple addition reactions, giving mixtures of the 3-alkylcycloalkenones and 1,3-dialkyl-3-(dialkylamino)cyclohexenes. In tetrahydrofuran, only the 3-alkylcycloalkenone was obtained. (C) 1997, Elsevier Science Ltd.

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页码：1547 / 1556

页数：10

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