Acute heart failure syndromes and coronary perfusion

被引：36

作者：

Beohar, Nirat ^{[1
]}

Erdogan, Ata K. ^{[1
]}

Lee, Daniel C. ^{[1
]}

Sabbah, Hani N. ^{[2
]}

Kern, Morton J. ^{[3
]}

Teerlink, John ^{[4
]}

Bonow, Robert O. ^{[1
]}

Gheorghiade, Mihai ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA

[2] Henry Ford Hlth Syst, Detroit, MI USA

[3] Univ Calif Irvine, Irvine, CA USA

[4] Univ Calif San Francisco, San Francisco, CA 94143 USA

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2008年 / 52卷 / 01期

关键词：

D O I：

10.1016/j.jacc.2008.03.037

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute heart failure syndromes (AHFS), with a high post-discharge mortality and rehospitalization rate, represent a significant public health burden. The treatment of patients hospitalized with AHFS often includes the use of vasoactive medications such as inotropes and vasodilators. Although such agents are frequently used, their safety and efficacy remain controversial. A significant number of patients with heart failure have underlying coronary artery disease and may be at greater risk from hemodynamic alterations that can diminish coronary perfusion. In AHFS, the relationship among vasoactive medications, coronary perfusion, and potential myocardial injury needs further investigation. Newer techniques now available to evaluate coronary perfusion should provide guidance for the evaluation of existing and future vasoactive therapies for AHFS.

引用

页码：13 / 16

页数：4

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