Chemical sensing in Drosophila

被引:52
作者
Benton, Richard [1 ]
机构
[1] Univ Lausanne, Fac Biol & Med, Ctr Integrat Genom, CH-1015 Lausanne, Switzerland
基金
欧洲研究理事会;
关键词
D O I
10.1016/j.conb.2008.08.012
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Chemical sensing begins when peripheral receptor proteins recognise specific environmental stimuli and translate them into spatial and temporal patterns of sensory neuron activity. The chemosensory system of the fruit fly, Drosophila melanogaster, has become a dominant model to understand this process, through its accessibility to a powerful combination of molecular, genetic and electrophysiological analysis. Recent results have revealed many surprises in the biology of peripheral chemosensation in Drosophila, including novel structural and signalling properties of the insect odorant receptors (ORs), combinatorial mechanisms of chemical recognition by the gustatory receptors (GRs), and the implication of Transient Receptor Potential (TRP) ion channels as a novel class of chemosensory receptors.
引用
收藏
页码:357 / 363
页数:7
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