Three-dimensional structure of annexins

被引：102

作者：

Liemann, S ^{[1
]}

Huber, R ^{[1
]}

机构：

[1] MAX PLANCK INST BIOCHEM,ABT STRUKTURFORSCH,D-82152 MARTINSRIED,GERMANY

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 1997年 / 53卷 / 06期

关键词：

annexin; crystal structure; electron microscopy; interfacial membrane proteins; ion channel;

D O I：

10.1007/s000180050065

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Annexins constitute a family of structurally related calcium- and phospholipid-binding proteins whose molecular structure has been investigated in detail in the crystalline and membrane-bound form. Their polypeptide chain is folded into four or eight alpha-helical domains of similar structure with a central hydrophilic pore. Bound to phospholipid membranes, the four-domain arrangement of the annexin molecule is conserved. A peripheral binding mode has been well documented by electron microscopy and a variety of other techniques.

引用

页码：516 / 521

页数：6

共 51 条

[11] A MODEL OF THE STRUCTURE OF HUMAN ANNEXIN-VI BOUND TO LIPID MONOLAYERS
DRIESSEN, HPC
NEWMAN, RH
FREEMONT, PS
CRUMPTON, MJ
[J]. FEBS LETTERS, 1992, 306 (01) : 75 - 79
[12] The high-resolution crystal structure of human annexin III shows subtle differences with annexin V
FavierPerron, B
LewitBentley, A
RussoMarie, F
[J]. BIOCHEMISTRY, 1996, 35 (06) : 1740 - 1744
[13] A CONSENSUS AMINO-ACID-SEQUENCE REPEAT IN TORPEDO AND MAMMALIAN CA-2+-DEPENDENT MEMBRANE-BINDING PROTEIN
GEISOW, MJ
FRITSCHE, U
HEXHAM, JM
DASH, B
JOHNSON, T
[J]. NATURE, 1986, 320 (6063) : 636 - 638
[14] COMMON DOMAIN-STRUCTURE OF CA-2+ AND LIPID-BINDING PROTEINS
GEISOW, MJ
[J]. FEBS LETTERS, 1986, 203 (01) : 99 - 103
[15] GUY H R, 1991, Biophysical Journal, V59, p372A
[16] 2 LIPOCORTIN-LIKE PROTEINS, ENDONEXIN-II AND ANCHORIN CII, MAY BE ALTERNATE SPLICES OF THE SAME GENE
HAIGLER, HT
FITCH, JM
JONES, JM
SCHLAEPFER, DD
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1989, 14 (02) : 48 - 50
[17] CRYSTAL AND MOLECULAR-STRUCTURE OF HUMAN ANNEXIN-V AFTER REFINEMENT - IMPLICATIONS FOR STRUCTURE, MEMBRANE-BINDING AND ION CHANNEL FORMATION OF THE ANNEXIN FAMILY OF PROTEINS
HUBER, R
BERENDES, R
BURGER, A
SCHNEIDER, M
KARSHIKOV, A
LUECKE, H
ROMISCH, J
PAQUES, E
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1992, 223 (03) : 683 - 704
[18] THE CRYSTAL AND MOLECULAR-STRUCTURE OF HUMAN ANNEXIN-V, AN ANTICOAGULANT PROTEIN THAT BINDS TO CALCIUM AND MEMBRANES
HUBER, R
ROMISCH, J
PAQUES, EP
[J]. EMBO JOURNAL, 1990, 9 (12) : 3867 - 3874
[19] THE CALCIUM-BINDING SITES IN HUMAN ANNEXIN-V BY CRYSTAL-STRUCTURE ANALYSIS AT 2.0 A RESOLUTION - IMPLICATIONS FOR MEMBRANE-BINDING AND CALCIUM-CHANNEL ACTIVITY
HUBER, R
SCHNEIDER, M
MAYR, I
ROMISCH, J
PAQUES, EP
[J]. FEBS LETTERS, 1990, 275 (1-2) : 15 - 21
[20] KARSHIKOV A, 1992, EUR BIOPHYS J BIOPHY, V20, P337, DOI 10.1007/BF00196592

← 1 2 3 4 5 6 →