Moving AHEAD with an international human epigenome project

被引:112
作者
Jones, Peter A. [1 ]
Archer, Trevor K. [2 ]
Baylin, Stephen B. [3 ]
Beck, Stephan [4 ]
Berger, Shelley [5 ]
Bernstein, Bradley E. [6 ]
Carpten, John D. [7 ]
Clark, Susan J. [8 ]
Costello, Joseph F. [9 ]
Doerge, Rebecca W. [10 ]
Esteller, Manel [11 ]
Feinberg, Andrew P. [12 ,13 ,14 ]
Gingeras, Thomas R. [15 ]
Greally, John M. [16 ]
Henikoff, Steven [17 ]
Herman, James G. [3 ]
Jackson-Grusby, Laurie [18 ]
Jenuwein, Thomas [19 ]
Jirtle, Randy L. [20 ]
Kim, Young-Joon [21 ]
Laird, Peter W. [1 ]
Lim, Bing [22 ]
Martienssen, Robert [23 ]
Polyak, Kornelia [24 ]
Stunnenberg, Henk [25 ]
Tlsty, Thea Dorothy [26 ]
Tycko, Benjamin [27 ]
Ushijima, Toshikazu [28 ]
Zhu, Jingde [29 ]
Pirrotta, Vincenzo [30 ]
Allis, C. David [31 ]
Elgin, Sarah C. [32 ]
Rine, Jasper [33 ]
Wu, Carl [34 ]
机构
[1] Univ So Calif, Kenneth Norris Jr Comprehens Canc Ctr, Los Angeles, CA 90089 USA
[2] NIEHS, NIH, Res Triangle Pk, NC 27709 USA
[3] Johns Hopkins Univ, Baltimore, MD 21231 USA
[4] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England
[5] Wistar Inst Anat & Biol, Philadelphia, PA 19104 USA
[6] Massachusetts Gen Hosp, Charlestown, MA 02129 USA
[7] TGen, Phoenix, AZ 85004 USA
[8] Garvan Inst Med Res, Sydney, NSW 2010, Australia
[9] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA
[10] Purdue Univ, W Lafayette, IN 47907 USA
[11] Spanish Natl Canc Ctr, Madrid, Spain
[12] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA
[13] Johns Hopkins Univ, Sch Med, Dept Oncol & Mol Biol, Baltimore, MD 21205 USA
[14] Johns Hopkins Univ, Sch Med, Dept Genet, Baltimore, MD 21205 USA
[15] Affymetrix, Santa Clara, CA 95051 USA
[16] Albert Einstein Coll Med, Bronx, NY 10461 USA
[17] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
[18] Harvard Univ, Sch Med, Boston, MA 02115 USA
[19] Res Inst Mol Pathol, A-1030 Vienna, Austria
[20] Duke Univ, Med Ctr, Durham, NC 27710 USA
[21] Yonsei Univ, Seoul 120719, South Korea
[22] Genome Inst Singapore, Singapore 138672, Singapore
[23] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
[24] Dana Farber Canc Inst, Boston, MA 02115 USA
[25] Radboud Univ Nijmegen, NL-6525 ED Nijmegen, Netherlands
[26] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94143 USA
[27] Columbia Univ, New York, NY 10032 USA
[28] Natl Canc Ctr, Tokyo 1040045, Japan
[29] Shanghai Canc Inst, Shanghai 200032, Peoples R China
[30] Rutgers State Univ, Piscataway, NJ 08854 USA
[31] Rockefeller Univ, New York, NY 10021 USA
[32] Washington Univ, St Louis, MO 63130 USA
[33] Univ Calif Berkeley, Berkeley, CA 94720 USA
[34] NCI, Bethesda, MD 20892 USA
关键词
D O I
10.1038/454711a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A plan to 'genomicize' epigenomics research and pave the way for breakthroughs in the prevention diagnosis and treatment of human disease. © 2008 Macmillan Publishers Limited. All rights reserved.
引用
收藏
页码:711 / 715
页数:5
相关论文
共 16 条
[1]   Chromatin signatures of pluripotent cell lines [J].
Azuara, V ;
Perry, P ;
Sauer, S ;
Spivakov, M ;
Jorgensen, HF ;
John, RM ;
Gouti, M ;
Casanova, M ;
Warnes, G ;
Merkenschlager, M ;
Fisher, AG .
NATURE CELL BIOLOGY, 2006, 8 (05) :532-U189
[2]   High-resolution profiling of histone methylations in the human genome [J].
Barski, Artern ;
Cuddapah, Suresh ;
Cui, Kairong ;
Roh, Tae-Young ;
Schones, Dustin E. ;
Wang, Zhibin ;
Wei, Gang ;
Chepelev, Iouri ;
Zhao, Keji .
CELL, 2007, 129 (04) :823-837
[3]   A bivalent chromatin structure marks key developmental genes in embryonic stem cells [J].
Bernstein, BE ;
Mikkelsen, TS ;
Xie, XH ;
Kamal, M ;
Huebert, DJ ;
Cuff, J ;
Fry, B ;
Meissner, A ;
Wernig, M ;
Plath, K ;
Jaenisch, R ;
Wagschal, A ;
Feil, R ;
Schreiber, SL ;
Lander, ES .
CELL, 2006, 125 (02) :315-326
[4]   Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project [J].
Birney, Ewan ;
Stamatoyannopoulos, John A. ;
Dutta, Anindya ;
Guigo, Roderic ;
Gingeras, Thomas R. ;
Margulies, Elliott H. ;
Weng, Zhiping ;
Snyder, Michael ;
Dermitzakis, Emmanouil T. ;
Stamatoyannopoulos, John A. ;
Thurman, Robert E. ;
Kuehn, Michael S. ;
Taylor, Christopher M. ;
Neph, Shane ;
Koch, Christoph M. ;
Asthana, Saurabh ;
Malhotra, Ankit ;
Adzhubei, Ivan ;
Greenbaum, Jason A. ;
Andrews, Robert M. ;
Flicek, Paul ;
Boyle, Patrick J. ;
Cao, Hua ;
Carter, Nigel P. ;
Clelland, Gayle K. ;
Davis, Sean ;
Day, Nathan ;
Dhami, Pawandeep ;
Dillon, Shane C. ;
Dorschner, Michael O. ;
Fiegler, Heike ;
Giresi, Paul G. ;
Goldy, Jeff ;
Hawrylycz, Michael ;
Haydock, Andrew ;
Humbert, Richard ;
James, Keith D. ;
Johnson, Brett E. ;
Johnson, Ericka M. ;
Frum, Tristan T. ;
Rosenzweig, Elizabeth R. ;
Karnani, Neerja ;
Lee, Kirsten ;
Lefebvre, Gregory C. ;
Navas, Patrick A. ;
Neri, Fidencio ;
Parker, Stephen C. J. ;
Sabo, Peter J. ;
Sandstrom, Richard ;
Shafer, Anthony .
NATURE, 2007, 447 (7146) :799-816
[5]  
CLARK SJ, 1994, NUCLEIC ACIDS RES, V22, P2990, DOI 10.1093/nar/22.15.2990
[6]   Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning [J].
Cokus, Shawn J. ;
Feng, Suhua ;
Zhang, Xiaoyu ;
Chen, Zugen ;
Merriman, Barry ;
Haudenschild, Christian D. ;
Pradhan, Sriharsa ;
Nelson, Stanley F. ;
Pellegrini, Matteo ;
Jacobsen, Steven E. .
NATURE, 2008, 452 (7184) :215-219
[7]   DNA methylation profiling of human chromosomes 6, 20 and 22 [J].
Eckhardt, Florian ;
Lewin, Joern ;
Cortese, Rene ;
Rakyan, Vardhman K. ;
Attwood, John ;
Burger, Matthias ;
Burton, John ;
Cox, Tony V. ;
Davies, Rob ;
Down, Thomas A. ;
Haefliger, Carolina ;
Horton, Roger ;
Howe, Kevin ;
Jackson, David K. ;
Kunde, Jan ;
Koenig, Christoph ;
Liddle, Jennifer ;
Niblett, David ;
Otto, Thomas ;
Pettett, Roger ;
Seemann, Stefanie ;
Thompson, Christian ;
West, Tony ;
Rogers, Jane ;
Olek, Alex ;
Berlin, Kurt ;
Beck, Stephan .
NATURE GENETICS, 2006, 38 (12) :1378-1385
[8]  
FEINBERG AP, WORKSH DEF EP ADDR V
[9]   A chromatin landmark and transcription initiation at most promoters in human cells [J].
Guenther, Matthew G. ;
Levine, Stuart S. ;
Boyer, Laurie A. ;
Jaenisch, Rudolf ;
Young, Richard A. .
CELL, 2007, 130 (01) :77-88
[10]   A blueprint for a human epigenome project: the AACR human epigenome workshop [J].
Jones, PA ;
Martienssen, R .
CANCER RESEARCH, 2005, 65 (24) :11241-11246