Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient

被引：57

作者：

Hurt, AC

Iannello, P

Jachno, K

Komadina, N

Hampson, AW

Barr, IG

McKimm-Breschkin, JL

机构：

[1] WHO, Collaborating Ctr Reference & Res Influenza, Parkville, Vic 3052, Australia

[2] CSIRO Mol & Hlth Technol, Parkville, Vic 3052, Australia

[3] Monash Univ, Sch Appl Sci, Churchill, Vic 3842, Australia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 05期

关键词：

D O I：

10.1128/AAC.50.5.1872-1874.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An influenza B virus from an infant with no history of treatment or contact with neuraminidase inhibitors demonstrated a significant reduction in sensitivity to these drugs. Here, we describe the analysis of a mixed viral population that contained a novel D197E amino acid substitution that was responsible for this reduction.

引用

页码：1872 / 1874

页数：3

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