Regulation of naive and memory T-cell homeostasis

被引：58

作者：

Surh, CD ^{[1
]}

Sprent, J ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 01期

关键词：

T-cells; homeostasis; cytokines;

D O I：

10.1016/S1286-4579(01)01509-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent work has confirmed the existence of homeostatic mechanisms that regulate the overall size and composition of the mature T-cell pool. Homeostatic mechanisms not only control total T-cell numbers but appear to act differently on naive vs. memory cells. The roles of self-MHC/pcp tide ligands and certain cytokines in T-cell homeostasis are discussed. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

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页码：51 / 56

页数：6

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