Isolation and characterization of new limonoid glycosides from Citrus unshiu peels

被引：16

作者：

Sawabe, A

Morita, M

Kiso, T

Kishine, H

Ohtsubo, Y

Minematsu, T

Matsubara, Y

Okamoto, T

机构：

[1] Kinki Univ, Inst Comprehens Agr Sci, Nara 6318505, Japan

[2] Kinki Univ, Joint Res Ctr, Higashiosaka, Osaka 5778502, Japan

[3] Sawai Pharmaceut Co Ltd, Dept Res, Asahi Ku, Osaka 5350004, Japan

[4] Kinki Univ, Fac Pharmaceut Sci, Higashiosaka, Osaka 5778502, Japan

[5] Kinki Univ, Fac Agr, Dept Agr Chem, Nara 6318505, Japan

来源：

CARBOHYDRATE RESEARCH | 1999年 / 315卷 / 1-2期

关键词：

limonoid glycosides; Citrus unshiu; methyl nomilinate 17-O-beta-D-glucopyranoside; B E constant linked scan FABMS;

D O I：

10.1016/S0008-6215(98)00328-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three limonoid glycosides were isolated from Citrus unshiu peels, and their structures were determined based on MS and NMR spectroscopic data as nomilinic acid 17-O-beta-D-glucopyranoside (1), methyl nomilinate 17-O-beta-D-glucopyranoside (2), and obacunone 17-O-beta-D-glucopyranoside (3). In particular, the location of the sugar moiety was clearly determined by the B/E constant linked scan FABMS method. No limonoid glycosides obtained here were found to have antitumor activity in NCI-H292 and EL-4 cell lines, (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：142 / 147

页数：6

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