Steroidal saponins from the bulbs of Lilium candidum

被引：73

作者：

Mimaki, Y

Satou, T

Kuroda, M

Sashida, Y

Hatakeyama, Y

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Tokyo 1920392, Japan

[2] Natl Inst Hlth Sci, Hokkaido Expt Stn Med Plants, Nayoro, Hokkaido 0960065, Japan

来源：

PHYTOCHEMISTRY | 1999年 / 51卷 / 04期

关键词：

Lilium candidum; liliaceae; bulbs; steroidal saponins; spirostanol saponins; furostanol saponin; Na+/K+ ATPase inhibition;

D O I：

10.1016/S0031-9422(99)00022-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Five new spirostanol saponins and a new furostanol saponin were isolated from the fresh bulbs of Lilium candidum. Their structures were elucidated on the basis of spectroscopic analysis, including two-dimensional NMR spectroscopic techniques and the result of acid hydrolysis. The isolated saponins contained a branched triglycoside moiety assigned as O-alpha-L-rhamnopyranosyl-(1 --> 2)-O-[beta-D-glucopyranosyl-(1 --> 6)]-beta-D-glucopyranose with the formation of an O-glycosidic linkage to C-3 of the aglycone as the common structural feature. The inhibitory activity of the saponins on Na+/K+ ATPase was evaluated. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：567 / 573

页数：7

共 21 条

[1] C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].