Cognitive and behavioural impairment in Parkinson's disease

被引:12
作者
Merims, Doron [2 ,3 ]
Freedman, Morris [1 ,2 ,3 ]
机构
[1] Mt Sinai Hosp, Dept Med, Div Neurol, Toronto, ON M6A 2E1, Canada
[2] Div Neurol, Toronto, ON, Canada
[3] Rotman Res Inst, Toronto, ON, Canada
关键词
D O I
10.1080/09540260802095123
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Although Parkinson's disease (PD) has been considered to primarily affect motor abilities, increasing emphasis is being placed on cognitive and behavioural impairment in this disorder. Depression, dementia, psychosis and impulse control disorders have a major impact on quality of life for both patients and families. This article reviews cognitive and behavioural disturbances in PD and their relation to affective and motor symptoms, treatment of dementia associated with PD, and treatment approaches to psychosis in PD. We also discuss similarities between the dementia of PD and dementia with Lewy bodies.
引用
收藏
页码:364 / 373
页数:10
相关论文
共 102 条
[71]   Effect of levodopa on cognitive function in Parkinson's disease with and without dementia and dementia with Lewy bodies [J].
Molloy, S. A. ;
Rowan, E. N. ;
O'Brien, J. T. ;
McKeith, I. G. ;
Wesnes, K. ;
Burn, D. J. .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2006, 77 (12) :1323-1328
[72]   Self-stimulatory behavior associated with deep brain stimulation in Parkinson's disease [J].
Morgan, JC ;
diDonato, CJ ;
Iyer, SS ;
Jenkins, PD ;
Smith, JR ;
Sethi, KD .
MOVEMENT DISORDERS, 2006, 21 (02) :283-285
[73]   Visual perception in Parkinson disease dementia and dementia with Lewy bodies [J].
Mosimann, UP ;
Mather, G ;
Wesnes, KA ;
O'Brien, JT ;
Burn, DJ ;
McKeith, IG .
NEUROLOGY, 2004, 63 (11) :2091-2096
[74]   Cognitive profile of patients with newly diagnosed Parkinson disease [J].
Muslimovic, D ;
Post, B ;
Speelman, JD ;
Schmand, B .
NEUROLOGY, 2005, 65 (08) :1239-1245
[75]   Comparison of dementia with Lewy bodies to Alzheimer's disease and Parkinson's disease with dementia [J].
Noe, E ;
Marder, K ;
Bell, KL ;
Jacobs, DM ;
Manly, JJ ;
Stern, Y .
MOVEMENT DISORDERS, 2004, 19 (01) :60-67
[76]   An algorithm (decision tree) for the management of Parkinson's disease (2001): Treatment guidelines [J].
Olanow, CW ;
Watts, RL ;
Koller, WC .
NEUROLOGY, 2001, 56 (11) :S1-S88
[77]   Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases [J].
Olson, EJ ;
Boeve, BF ;
Silber, MH .
BRAIN, 2000, 123 :331-339
[78]   Relationship between hallucinations, delusions, and rapid eye movement sleep behavior disorder in Parkinson's disease [J].
Pacchetti, C ;
Manni, R ;
Zangaglia, R ;
Mancini, F ;
Marchioni, E ;
Tassorelli, C ;
Terzaghi, M ;
Ossola, M ;
Martignoni, E ;
Moglia, A ;
Nappi, G .
MOVEMENT DISORDERS, 2005, 20 (11) :1439-1448
[79]   Parkinson's disease and apolipoprotein E: Possible association with dementia but not age at onset [J].
Parsian, A ;
Racette, B ;
Goldsmith, LJ ;
Perlmutter, JS .
GENOMICS, 2002, 79 (03) :458-461
[80]   IS THERE A PREMORBID PERSONALITY TYPICAL FOR PARKINSONS-DISEASE [J].
PAULSON, GW ;
DADMEHR, N .
NEUROLOGY, 1991, 41 (05) :73-76