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Ulcerative colitis

被引：160
作者：
Farrell, RJ [1 ]
Peppercorn, MA [1 ]
机构：
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis,Div Gastroenterol, Boston, MA 02215 USA
来源：
LANCET | 2002年 / 359卷 / 9303期
关键词：
D O I：
10.1016/S0140-6736(02)07499-8
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Ulcerative colitis is a chronic inflammatory disease of the rectum and colon. Results from many studies in people and animals of intestinal inflammation suggest that ulcerative colitis results from environmental factors triggering a loss of tolerance for normal intestinal flora in genetically susceptible individuals. Although progress has been made in the overall management of the disease, no innovative treatment has been developed. By contrast with Crohn's disease, there are few clinical data on biological agents. Probiotics seem the most promising of several experimental and traditional agents that have been investigated in controlled clinical trials.
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页码：331 / 340
页数：10
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