Identifying bacteria in human urine: Current practice and the potential for rapid, near-patient diagnosis by sensing volatile organic compounds

被引:39
作者
Guernion, N
Ratcliffe, NM
Spencer-Phillips, PTN
Howe, RA
机构
[1] Univ W England, Fac Sci Appl, Bristol BS16 1QY, Avon, England
[2] Bristol Ctr Antimicrobial Res & Evaluat, Southmead Hlth Serv NHS Trust, Bristol, Avon, England
关键词
urinary tract infection; microorganisms; gas sensors; microbiological techniques; electronic nose technology;
D O I
10.1515/CCLM.2001.146
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Urinary tract infection (UTI) represents a significant burden for the National Health Service. Extensive research has been directed towards rapid detection of UTI in the last thirty years. A wide range of microbiological and chemical techniques are now available to identify and quantify bacteria in urine. However, there is a clear and present need for near, rapid, sensitive, reliable analytical methods, preferably with low-running costs, that could allow early detection of UTI and other diseases in urine. Here we review the "state of the art" of current practice for the detection of bacteria in urine and describe the advantages of the recent "e-nose" technology as a potential tool for rapid, near-patient diagnosis of UTI, by sensing volatile organic compounds (VOCs).
引用
收藏
页码:893 / 906
页数:14
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