Ceftriaxone-related hemolysis and acute renal failure

被引：24

作者：

Demirkaya, E ^{[1
]}

Atay, AA

Musabak, U

Sengul, A

Gok, F

机构：

[1] Gulhane Mil Med Acad, Dept Pediat Nephrol, TR-06018 Ankara, Turkey

[2] Gulhane Mil Med Acad, Dept Immunol, TR-06018 Ankara, Turkey

来源：

PEDIATRIC NEPHROLOGY | 2006年 / 21卷 / 05期

关键词：

ceftriaxone; immune hemolytic anemia; tubulointerstitial nephritis; acute renal failure; direct antiglobulin test;

D O I：

10.1007/s00467-006-0043-4

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A 5-year-old girl with no underlying immune deficiency or hematologic disease was treated with a combination of ceftriaxone and ampicilline-sulbactam for pneumonia. On the ninth day of the therapy, she developed oliguria, paleness, malaise, immune hemolytic anemia (IHA) and acute renal failure (ARF). Laboratory studies showed the presence of antibodies against ceftriaxone. Acute interstitial nephritis (AIN) was diagnosed by renal biopsy. The patient's renal insufficiency was successfully treated with peritoneal dialysis without any complications. The patient recovered without any treatment using steroids or other immunosuppressive agents.

引用

页码：733 / 736

页数：4

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