Elevated serum haptoglobin in pigs infected with porcine reproductive and respiratory syndrome virus

被引：79

作者：

Asai, T ^{[1
]}

Mori, M ^{[1
]}

Okada, M ^{[1
]}

Uruno, K ^{[1
]}

Yazawa, S ^{[1
]}

Shibata, I ^{[1
]}

机构：

[1] Zennoh Inst Anim Hlth, Sakura, Chiba, Japan

来源：

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 1999年 / 70卷 / 1-2期

关键词：

porcine reproductive and respiratory syndrome; haptoglobin; interleukin-6; pigs;

D O I：

10.1016/S0165-2427(99)00069-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We examined the two acute phase proteins, alpha (alpha)-1 acid glycoprotein (AGP) and haptoglobin (HP), in serum of pigs following experimental porcine reproductive and respiratory syndrome (PRRS) virus infection. Increased levels of serum HP, but not AGP, were observed from 7 to 21 days post-inoculation in the infected pigs. Furthermore, serum IL-6 increased in the infected pigs, but TNF-alpha did not. The increase of serum IL-6 in pigs following PRRS virus infection may induce production of HP. Also, in the field investigation, serum HP in pigs was dramatically increased after exposure to the PRRS virus. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：143 / 148

页数：6

共 21 条

[1] Immune responses in pigs infected with porcine reproductive and respiratory syndrome virus (PRRSV) [J].