Molecular approaches to field studies of malaria

被引:1
作者
Beck, Hans-Peter [1 ]
Tetteh, Kevin [2 ]
机构
[1] Swiss Trop Inst, CH-4002 Basel, Switzerland
[2] London Sch Hyg & Trop Med, Dept Infect & Trop Dis, Pathogen Mol Biol Unit, London WC1E 7HT, England
关键词
D O I
10.1016/j.pt.2008.09.004
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The third 'Molecular Approaches to Malaria' conference was held in Lorne, Australia, in February 2008 and provided extensive information on the application of molecular tools in field studies on malaria. In recent years, technological advances and capacity building in malaria-endemic countries have permitted molecular tools to be applied much more frequently and successfully with exciting new findings. In this review, Hans-Peter Beck and Kevin Tetteh report on the most recent findings using molecular tools in field studies.
引用
收藏
页码:585 / 589
页数:5
相关论文
共 53 条
[1]   Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (Encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase), tctp, mdr1, and cg10 [J].
Afonso, A ;
Hunt, P ;
Cheesman, S ;
Alves, AC ;
Cunha, CV ;
do Rosário, V ;
Cravo, P .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (02) :480-489
[2]   Population Genomics of the immune evasion (var) genes of Plasmodium falciparum [J].
Barry, Alyssa E. ;
Leliwa-Sytek, Aleksandra ;
Tavul, Livingston ;
Imrie, Heather ;
Migot-Nabias, Florence ;
Brown, Stuart M. ;
McVean, Gilean A. V. ;
Day, Karen P. .
PLOS PATHOGENS, 2007, 3 (03)
[3]   A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya [J].
Bejon, Philip ;
Mwacharo, Jedidah ;
Kai, Oscar ;
Mwangi, Tabitha ;
Milligan, Paul ;
Todryk, Stephen ;
Keating, Sheila ;
Lang, Trudie ;
Lowe, Brett ;
Gikonyo, Caroline ;
Molyneux, Catherine ;
Fegan, Greg ;
Gilbert, Sarah C. ;
Peshu, Norbert ;
Marsh, Kevin ;
Hill, Adrian V. S. .
PLOS CLINICAL TRIALS, 2006, 1 (06)
[4]   The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin [J].
Bhisutthibhan, J ;
Pan, XQ ;
Hossler, PA ;
Walker, DJ ;
Yowell, CA ;
Carlton, J ;
Dame, JB ;
Meshnick, SR .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (26) :16192-16198
[5]  
Bian ZQ, 2000, CHINESE MED J-PEKING, V113, P981
[6]   Safety and immunogenicty of RTS,S/AS02A candidate malaria vaccine in Gambian children [J].
Bojang, KA ;
Olodude, F ;
Pinder, M ;
Ofori-Anyinam, O ;
Vigneron, L ;
Fitzpatrick, S ;
Njie, F ;
Kassanga, A ;
Leach, A ;
Milman, J ;
Rabinovich, R ;
McAdam, KPWJ ;
Kester, KE ;
Heppner, DG ;
Cohen, JD ;
Tornieporth, N ;
Milligan, PJM .
VACCINE, 2005, 23 (32) :4148-4157
[7]   Plasmodium falciparum antigenic variation.: Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks [J].
Bull, Peter C. ;
Buckee, Caroline O. ;
Kyes, Sue ;
Kortok, Moses M. ;
Thathy, Vandana ;
Guyah, Bernard ;
Stoute, Jose A. ;
Newbold, Chris I. ;
Marsh, Kevin .
MOLECULAR MICROBIOLOGY, 2008, 68 (06) :1519-1534
[8]   No genetic bottleneck in Plasmodium falciparum wild-type pfcrt alleles reemerging in Hainan Island, China, following high-level chloroquine resistance [J].
Chen, Nanhua ;
Gao, Qi ;
Wang, Shanqing ;
Wang, Guangze ;
Gatton, Michelle ;
Cheng, Qin .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (01) :345-347
[9]   Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin [J].
Cholera, Rushina ;
Brittain, Nathaniel J. ;
Gillriet, Mark R. ;
Lopera-Mesa, Tatiana M. ;
Diakite, Seidina A. S. ;
Arie, Takayuki ;
Krause, Michael A. ;
Guindo, Aldiouma ;
Tubman, Abby ;
Fujioka, Hisashi ;
Diallo, Dapa A. ;
Doumbo, Ogobara K. ;
Ho, May ;
Wellems, Thomas E. ;
Fairhurst, Rick M. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (03) :991-996
[10]   Rapid micro array-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria drugs [J].
Crameri, Andreas ;
Marfurt, Jutta ;
Mugittu, Kefas ;
Maire, Nicolas ;
Regoes, Attila ;
Coppee, Jean Yves ;
Sismeiro, Odile ;
Burki, Richard ;
Huber, Eric ;
Laubscher, Daniel ;
Puijalon, Odile ;
Genton, Blaise ;
Felger, Ingrid ;
Beck, Hans-Peter .
JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (11) :3685-3691