Domain definition and target classification for CASP6

被引：20

作者：

Tress, M

Tai, CH

Wang, G

Ezkurdia, I

López, G

Valencia, A

Lee, B

Dunbrack, RL

机构：

[1] Fox Chase Canc Ctr, Inst Canc Res, Philadelphia, PA 19111 USA

[2] CSIC, CNB, Prot Design Grp, Canto Blanco 28049, Spain

[3] NIH, Mol Modeling & Bioinformat Sect, Lab Nol Modeling, Canc Res Ctr, Bethesda, MD 20892 USA

来源：

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | 2005年 / 61卷

关键词：

D O I：

10.1002/prot.20717

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Assessment of structure predictions in CASP6 was based on single domains isolated from experimentally determined structures, which were categorized into comparative modeling, fold recognition, and new fold targets. Domain definitions were defined upon visual examination of the structures with the aid of automated domain-parsing programs. Domain categorization was determined by comparison of the target structures with those in the Protein Data Bank at the time each target expired and a variety of sequence and structure-based methods to determine potential homologous relationships.

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页码：8 / 18

页数：11

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