Changes in brain anatomy in focal hand dystonia

被引：114

作者：

Garraux, G

Bauer, A

Hanakawa, T

Wu, T

Kansaku, K

Hallett, M

机构：

[1] NINDS, Human Motor Control Sect, Med Neurol Branch, NIH, Bethesda, MD 20892 USA

[2] Univ Liege, Cyclotron Res Ctr, Liege, Belgium

[3] Univ Liege, Dept Neurol, Liege, Belgium

来源：

ANNALS OF NEUROLOGY | 2004年 / 55卷 / 05期

关键词：

D O I：

10.1002/ana.20113

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

No consistent cerebral anatomical abnormality has ever been reported in primary focal hand dystonia (FHD). The present voxel-based morphometry study showed a significant bilateral increase in gray matter in the hand representation area of primary somatosensory and, to a lesser extent, primary motor cortices in 36 patients with unilateral FHD compared with 36 controls. The presence of anatomical changes in the perirolandic cortex for the unaffected hand as well as that for the affected hand suggests that these disturbances may be, at least in part, primary.

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页码：736 / 739

页数：4

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